A study conducted in 2012 showed that CBN had a noticeably stimulating effect on the appetite of mammals. It was observed that CBN increased appetite, resulted in a shorter period of time between meals, and also increased the meal size and duration of each meal. This information is especially interesting for someone who may have a reduced appetite due to chemotherapy, or other factors.
Cannabinol, or CBN, is a mildly psychoactive derivative of the cannabinoid THCa (tetrahydrocannabinolic acid), and is created when THCa oxidizes. The term oxidation refers to the process by which a substance combines with oxygen, to create a different substance. This process occurs when cannabis degrades, as a result of being exposed to heat or oxygen.
One particular condition which has generated some excitement for CBN is glaucoma. This is because CBN acts as a “vasorelaxant”, which is a fancy term for relaxing blood vessel walls and decreasing blood pressure. In the eyes, CBN increases blood flow and reduces the pressure associated with glaucoma.”3
Numerous studies have been conducted which point to CBN being a powerful reliever of intraocular pressure. It was observed that a strong dosing of CBN may lower ocular tension considerably. “Like CBD, CBN modulates the levels of endocannabinoids. It influences specific immune cells to produce anti-inflammatory effects and impacts levels of other compounds known to cause inflammation.
Studies show that CBN can aid in pain relief as it interacts directly with pain signals sent to the brain. This is the result of the CB1 cannabinoid receptors being present in the pain pathway of the nervous system. This allows for CBN and other cannabinoids to relieve inflammation and pain in the body.
CBN has shown great promise in a variety of studies, one of those being CBN’s antibacterial properties and ability to fight MRSA, a bacteria that is particularly resistant to antibiotics. “All five major cannabinoids (cannabidiol, cannabichromene, cannabigerol, Delta (9)-tetrahydrocannabinol, and cannabinol showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains of current clinical relevance.”2
CBN is the most effective cannabinoid observed for sleep, making it an increasingly common choice for those with insomnia. Studies have shown that CBN works as a sedative to help reduce the time it takes to fall asleep, and can extend the duration of time asleep. These effects are significantly more apparent when pairing CBN with THC.