Water-Soluble vs. Oil-Soluble CBD : What You Need To Know Hemp-derived CBD oil has gone mainstream. CBD, also known as cannabidiol, is an incredibly beneficial plant compound derived from Hemp. Although not everyone knows about it yet, the vast majority of people out there that have heard about it associate it with oil In this article, you'll learn the key benefits of water-soluble CBD, and how it measures up to other forms of CBD on the market, specifically about its bioavailability. Water Soluble CBD is better absorbed by the body when swallowed. When swallowed, CBD in oil form only has 10-20% bioavailability. That means if you take a 20mg dose, you might only be absorbing 2-4mg of actual CBD. In order to consume CBD oil properly, you have to hold it under your tongue, absorbing it sublingually.
Water-Soluble vs. Oil-Soluble CBD : What You Need To Know
CBD, also known as cannabidiol, is an incredibly beneficial plant compound derived from Hemp. Although not everyone knows about it yet, the vast majority of people out there that have heard about it associate it with oil. They may imagine any of the popular oil-based products such as tinctures, creams, and vapes.
We all know that oil and water don’t mix well. This reality makes things a bit tricky for CBD and other oil-soluble plant extracts because most products and supplements we use are not oil-based.
What most people don’t know is that CBD, in its natural oil form, can only be effectively incorporated into the body through a narrow range of uses. Common oil-based delivery methods, like tinctures, are not meant to be swallowed, and for good reason.
It all comes down something known as bioavailability, which indicates how much of any given substance is actually able to be absorbed by the body. There’s one bodily process in particular that’s responsible for preventing the effective uptake of CBD oil in the stomach.
First Pass Metabolism
First-pass metabolism (also referred to as the first-pass effect) is a physiological phenomena in drug (plant extract) delivery science where the concentration of a compound is greatly reduced before it reaches systemic circulation.
This concentration reduction means a decrease in bioavailability, and is a relatively common problem that affects a huge range of compounds including, morphine, curcumin (from turmeric), lidocaine, nitroglycerin, and many found in cannabis.
CBD can’t effectively make it through hepatic portal vein system when swallowed in it’s natural oil state.
First-pass metabolism only affects the bioavailability of CBD when consumed orally, and there are some creative chemistry techniques used to get around it.
Luckily, rubbing CBD into your skin, dropping some tincture under your tongue, or hitting a vape pen allows the CBD to directly enter systemic circulation. These delivery methods don’t go near any of the mechanisms associated with the first-pass effect, and bioavailability is not negatively affected.
What’s the problem?
The issue still remains that we cannot effectively absorb CBD when swallowed in it’s natural oil state.
You might be thinking, “What about all the CBD capsules and drinks out there? Am I not actually getting the full dose that’s advertised?” The answer to those questions all depend on the method used to formulate the CBD extract.
As we learned above, the first pass effect greatly decreases the bioavailability of CBD oil when swallowed. So, unfortunately, nearly all CBD-oil capsules that you see on the market will have very poor absorption rates. That translates to taking a 20mg capsule and only actually absorbing around 5mg!
Luckily, brilliant scientists have already addressed this problem and have devised ways to effectively overcome the first pass effect.
They’ve developed novel chemistry techniques that are now common in drug delivery science and are super important because almost 40% of new drug compounds are hydrophobic and have the same oral bioavailability issues as CBD. [source]
Enter Water-Soluble CBD…
One of the primary ways to overcome the first-pass effect is to convert the naturally oil-soluble CBD extract into a water-soluble form. This makes total sense, especially when considering the fact that the average adult is somewhere from 50–60% water.
WE ARE WATER | Photo by Amritanshu Sikdar
So how does this happen? Well, the technique that we use at UnCanny Wellness is known as Self-Emulsifying Drug Delivery System [SEDDS], and possesses unparalleled potential in improving oral bioavailability of poorly water-soluble drugs. [source]
Basically, you can think of CBD extract in oil form is a big blob (very scientific, I know). When this blob of oil enters your stomach it’s too large to pass through your gut lining and enter systemic circulation without being broken down by enzymes and passed along the the liver for processing.
By converting the oil to a water-soluble powder, the oil-blob is broken down into tiny, micro-sized pieces. These pieces of oil are very, very small, and are encapsulated within other non-toxic materials to ensure they remain stable in this new form. The end result of this process is an off-white, water-soluble, micro-encapsulated, full-spectrum, CBD hemp extract.
This conversion process completely overcomes the first-pass effect, and allows CBD oil (and other similar compounds) to be consumed orally without sacrificing bioavailability.
Why should you care?
Converting CBD oil to a water-soluble powder greatly increases the ways in which it can be used. Not everyone wants to hold a tincture under their tongue or hit a vape pen in order to get their dose of CBD.
When we take a look what’s on the shelves of health and wellness aisles in natural food stores, we can see that there are an overwhelmingly large amount of capsules and drink-powders. Only by converting CBD oil into a water-soluble powder can we effectively incorporate CBD into these types of products.
Water-soluble CBD powder opens up a world of possibilities. Not only does it allow us to effectively use capsules as a form of precise CBD delivery, but it also lets us use CBD in any drink or food product we can imagine.
CBD & Coffee — a lovely combination | Photo by Wu Yi
Want to infuse CBD into your pasta sauce? Sure.
How about throwing some CBD into that latte? No problem at all.
CBD in your smoothie? Done deal.
As you can see, water-soluble CBD powder has endless potential. It makes the most sense for widespread adoption and use in our everyday lives. Sure, you could just drop some CBD oil into any of the examples above. But how much would you actually be absorbing? Not much at all…
It would be like paying for a full tank of gas and only getting 10–20%. That’s simply unacceptable.
Supplementing your wellness routine with a powerful plant compound like CBD does not need to be a chore. As a species, we’ve grown up with the cannabis plant, and hemp has played such an important role in our history.
We all contain an incredibly complex and important endocannabinoid system in our body that helps to regulate the function of our nervous and immune systems. Activating this system with CBD supplementation is something that nearly everyone can benefit from.
It’s time to start firing that system up with water-soluble CBD !
Is Water-Soluble CBD Better? A deeper look
Drinking water-soluble CBD is one of the many ways you can take CBD. As a refresher, CBD is one of 113 cannabinoids found in the hemp plant. In this article, you’ll learn the key benefits of water-soluble CBD, and how it measures up to other forms of CBD on the market.
WHAT IS WATER-SOLUBLE CBD?
Water-soluble CBD is CBD oil that has been broken through a 4-step process into fine crystalline particles, making it easier to be absorbed. Being easily absorbed, the CBD powder form of CBD extract can easily be ingested by mixing into drinks or food.
Being easily absorbed, the CBD powder form of CBD extract can easily be ingested by mixing into drinks or food.
WATER-SOLUBLE CBD VS. CBD OIL
When researching water-soluble CBD on the Internet, you might find that water-soluble CBD and CBD oil are commonly compared. CBD oil is one of the more popular ways to take CBD, so it’s important to see how water-soluble CBD stacks up. The biggest differences between the two are their physical format and bioaccessibility, or absorption rate.
STRUCTURE AND TASTE
Water-soluble CBD is in powder form, while CBD oil is, well, in oil form. Both can be taken orally, however pure CBD oil has an earthy taste that might not be for everyone. Water-soluble CBD powder often doesn’t taste like hemp, and can even come in fruit-infused flavors like Tropical Orange or Passion Fruit in Well+.
Another key difference between water-soluble CBD vs. CBD oil is absorption rate. Water-soluble CBD is known to have a higher absorption rate than other forms of CBD. This is because the CBD has been broken down into even smaller particles that can be easily absorbed by the body. For example, when you take 20mg of CBD oil, you will typically absorb 10-20% of the CBD that was ingested. On the other hand, water-soluble CBD such as Zolt has bioavailability that is 5 times higher than other CBD formats. That means you can absorb 90% of the CBD you are ingesting with water-soluble form of CBD. Pretty cool, right?
HOW TO USE WATER-SOLUBLE CBD
The beauty of water-soluble CBD is that you can mix it into just about anything. With Zolt water-soluble mixie sticks, we recommend mixing the powder with 16oz of water (hot or cold) and stirring with gusto. We’ve heard from our customers that they use our CBD powder in lemonade, smoothies, cocktails, or in a CBD tea.
TYPES OF WATER -SOLUBLE CBD
When you’re looking into buying water-soluble CBD, you might come across two different types of products: hemp CBD isolate and full-spectrum hemp. It’s important to know the difference between the two, so you know exactly what you’re taking.
CBD isolate is pure CBD with no additional compounds, which means that it doesn’t contain active compounds like other cannabinoids, flavonoids, and terpenes. One major cannabinoid that CBD isolate does not contain is THC. Some people opt for CBD Isolate because it has no trace of THC. One downside of CBD isolate is that you won’t get the entire benefit of the plant, known as the entourage effect, a term used to describe the synergistic effect of the full range of cannabinoids and hemp biomolecules working together.
Full-spectrum hemp includes the full-range of cannabinoids in the hemp plant, including a trace level of THC (less than 0.3%). With full-spectrum water-soluble hemp, you get the full benefits of hemp’s active compounds that work together to achieve a balance of mind and body. This is called the entourage effect. Some CBD companies offer hemp CBD isolate and full-spectrum hemp product lines. On the Zolt site, you can identify our full-spectrum CBD by looking for those that are marked + after the product name.
CHOOSING THE RIGHT ONE FOR YOU
When choosing certain CBD products, it’s really up to personal preference. A good rule of thumb is to start with a small dose of the CBD product, see how you feel, and increase from there. We recommend starting with the Zolt Variety Pack to try out different flavors. It includes both CBD isolate and full-spectrum CBD, so you can explore which CBD type is the right fit.
4 Reasons Water Soluble CBD is Better Than Oil
If you’ve made it far enough in your search to read this article, you’ve at least heard about water soluble CBD. Maybe you’ve seen a bottle of water infused with CBD for sale, or something like the capsules and powders we sell here at UnCanny Wellness.
But do you actually understand why water soluble CBD is better than normal CBD oil?
Most of the products available out there today are oil-based. Tinctures, creams, salves, vapes. all oil-based products. The literal CBD oil is simply an ingredient in those varying formulations.
We have to remember that this industry is very young, and it’s only a couple years ago that people were literally selling plastic syringes full of raw CBD oil. Let me tell you, that is some intensely bitter, foul tasting stuff!
Water soluble CBD is going to be a huge part of the future of CBD product development. Once you understand why it becomes clear. Here are the 4 important reasons why water soluble CBD is better than CBD oil.
Water Soluble CBD is better absorbed by the body when swallowed. When swallowed, CBD in oil form only has 10-20% bioavailability. That means if you take a 20mg dose, you might only be absorbing 2-4mg of actual CBD. In order to consume CBD oil properly, you have to hold it under your tongue, absorbing it sublingually.
Luckily, this problem of absorption when swallowed (oral bioavailability) is relatively common in drug delivery science. Lot’s of drug compounds are naturally oil-soluble. Techniques have been developed to convert these from an oil into a format that is better absorbed in the body and easier to administer.
Using these special techniques to convert the CBD from being oil-soluble to water-soluble means that you can just swallow the CBD and your body will absorb more of it, increasing the desired effects.
CBD oil can only mix in with other oils. That’s what oil-soluble means. But most of what’s out there that you’d want to incorporate CBD into is not an oil. Coffee, tea, water, juice, smoothies, dog food – all of that is going into the stomach and therefore requires a form of CBD that can be effectively absorbed in the stomach.
If you’ve ever tried to mix CBD oil into a cup of tea, or a cocktail, you quickly find out that it doesn’t work. The oil floats to the top and sticks to the sides, it tastes terrible, and then after going through all the trouble to swallow it down you only absorb a fraction of the actual dose you’re expecting. Please don’t be that person.
Because CBD is more more bioavailable when swallowed than oil, it means you can take less and absorb more – it’s more potent. For example, if you swallowed a 10mg CBD oil-filled capsule you might only be absorbing 1-2mg of CBD – but if you swallowed a 10mg dose of a water soluble CBD-filled capsule you will be absorbing 9-10mg!
This is particularly important to understand when choosing the right product. So many companies out there sell cheap oil-based products at a premium just because they have high mg dosage and some shiny branding. Let’s be real, CBD products can be expensive and you deserve to get the most potent product that will work the best for you.
4) More User Friendly
If you walk into the health department of any store and you’ll see that it’s dominated by pills and powders. There might be a bit of shelf space dedicated to oil-based herbal tinctures, but people clearly prefer to consume their superfoods and supplements in pill or powder form. It’s just so much easier.
Most people out there, probably you included, would rather not hold an oil-based tincture under their tongue. It can be pretty gross tasting and isn’t very uncomfortable. Alternatively, a water soluble CBD capsule effortlessly fits into anyones existing vitamin or supplement routine. Or in powder form, you can easily infuse any of your favorite drinks and foods that you already love to consume, at whatever dose you need at that time.
At the end of the day it’s all about getting high quality CBD to more people so that they can feel b etter and live a better life. We’re all burdened with something ‘off’ from time to time, whether it’s feeling overwhelmed with the state of the world, muscle soreness after a workout or aching joints from a long life well lived.
Using the the right quality products is key to supporting your self and your loved ones, and water soluble CBD products are more effective and easier to use than CBD oil products.