The reduction of iNOS and reactive oxygen species by CBD, along with the reduction of lipid peroxidation, shows the important therapeutic action of CBD in reduction of colonic inflammation by indirect reduction of oxidative damage. In addition, the dysregulation of the interleukins IL-1B and IL-10 is a well-known disruption caused by irritable bowel disease (IBD). The restoration of these interleukins to normal behavior by CBD, although the specific pathway is unknown, is another important therapeutic action that CBD has on reduction of colonic inflammation.
But CBD has other effects on your endocrine system, particularly your appetite. You may simply think that marijuana produces the munchies and therefore makes you fat, and although this makes logical sense, science has shown that it’s not the case that marijuana makes you fat, especially when CBD is present.
As a matter of fact, leading up to this article, I’ve used very high amounts of CBD (100+mg) with no ill effect, aside from extreme feelings of relaxation, calm and the impression that if my home caught on fire, I probably wouldn’t care (OK, so maybe that’s an ill effect).
The Effects Of CBD On Metabolism & Body Fat
You’ve already seen the data on the big cortisol-lowering effects of CBD. But when it comes to anxiety and paranoia in general, a THC-rich strain of marijuana will actually increase not decrease stress unless there is enough CBD present to balance out the stress-increasing effect of weed.
It’s also nearly impossible to overdose on CBD. Kind of like water, dark chocolate, and steamed kale, it has an unusually low level of toxicity. In the last 6,000 years, CBD hasn’t killed anyone via overdose, which is particularly impressive when you compare it to non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, Advil and Tylenol, which can wreak havoc on your gut lining, liver and kidneys. Or aspirin (salicylic acid) which kills over 1,000 people every year. Or alcohol, which kills over 110,000 people a year. No one’s ever died from CBD.
India is the main cultivator of all the world’s turmeric crops and consumes 80% of the world’s supply. Due to the high content of the main bioactive component in turmeric (curcumin) Indian turmeric is considered to be the best in the world for medicinal purposes. The Indian city of Erode, located in the South Indian State of Tamil Nadu, is the trading hub for turmeric in the Eastern hemisphere. Erode is so well known for its turmeric production that it is referred to as “Yellow City,” and “Turmeric City” (similar to the way that my living room couch is covered in yellow stains from my frequent turmeric sprinkling on most of the dinners I eat).
While medical marijuana is grown to be high in CBD for the treatment of specific ailments, the THC content can vary dramatically, sometimes getting as high as the CBD content. The other problem with medical marijuana (besides the possibility of getting a strain that is high in THC) is that it’s not currently legal everywhere. In the United States, you must be living in certain states and obtain a prescription from a doctor to receive medical marijuana.
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