On that note, Hill cautions to know what you’re getting: “If you’re rubbing a CBD cream onto your skin, it’s not going to be absorbed into your bloodstream,” he says. “It can operate as a local anti-inflammatory, like other over-the-counter products… but CBD may not provide any more relief than those products, and it probably will be considerably more expensive.”
The cannabis plant has hundreds of chemicals in it, including more than 120 cannabinoids, Hill explains. Of those cannabinoids, two are most familiar: THC, which produces the euphoric effects or “high” people experience from marijuana, and cannabidiol or CBD, which has some anti-inflammatory, anti-seizure, anxiety-relieving and analgesic properties, according to Low Dog.
“Quality is always an issue, especially in a relatively young market, such as the cannabis market,” Low Dog says. And she’s right. A 2017 study published in the Journal of the American Medical Association found that out of the commercially available CBD products, only 30 percent were accurately labeled.
CBD tincture vs. CBD oil—which is better?
At a plant level, the two chemicals operate as opposites, with CBD acting as a buffer of sorts to the effects of THC. “It’s sort of a ying and yang. THC is responsible for the high and CBD doesn’t do that,” Hill explains.
“At the end of the day [CBD] is a fairly safe compound,” Hill says. “Although, we still need to know a lot more about it, like how it interacts with other medications people may be taking and what are the long-term effects,” he adds. And perhaps his biggest concern: “Sometimes people want to use it instead of evidence-based treatment and that can be a problem clinically in certain situations.”
“Sometimes, you will find extracts called tinctures that use glycerin, vinegar, or oil as the solvent, instead of alcohol,” Low Dog says. “These offer the advantage of being alcohol-free, but may not always offer the same potency as an alcohol-water extract.”
Despite its relatively recent place in our collective consciousness, CBD has been at work delivering its calming agents as far back as the ‘80s by some estimates and the ancient world by others. With it, an almost endless menu of formulations has emerged—from capsules and oils to lotions and seltzer—each promising an even more effective dose of CBD than the last.
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit.
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Is cannabidiol legal?
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a "high." According to a report from the World Health Organization, "In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD."
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?