Some of the same criteria that controls how long it takes for CBD’s effects to begin also determines how long those effects will last. For instance, it makes sense that a smaller dose will leave your system faster than a larger dose. Also, ingestible products may seem to last longer because they take longer to kick in.
Among wellness products, you’d be hard-pressed to find one that’s as versatile and adaptable as CBD. There’s essentially a product for everyone, with variations in delivery mechanisms and flavors that cater to even the most discriminate users and palates.
These days, it is everywhere you look. It’s on shelves in the drug store, television screens, roadside billboards, and, of course, the internet. Your parents might have asked you about it. Your grandparents might have even asked you about it. It is cannabidiol, also known as CBD, and it’s arguably the hottest wellness trend to hit the scene in years.
How long do the effects of CBD last?
The first study of interest, an account completed by researchers at Drake University and the University of Wisconsin, claims that the half-life of orally administered CBD is about 1 to 2 days. However, another study conducted on Huntington’s disease patients, surmised that the elimination half-life of CBD ranged from 2 to 5 days.
Delivery mechanisms describe the way in which someone consumes CBD. Some users opt to vape CBD, utilizing a device called a vape pen that can heat CBD oils into vapor. While many medical experts have spoken out against the dangers of vaping — including Dr. Anne Schuchat, principal deputy director of the Centers for Disease Control and Prevention — vaporizing may allow someone to feel the effects of the CBD faster.
Those benefits are possible because of a regulatory, cell-signaling system in our bodies called the endocannabinoid system (ECS). Though it plays a vital part in how our systems operate daily, the ECS is a relatively new concept. In fact, researchers only started investigating what it does and how it works in the 1990s.
CB1 receptors have a significant presence in our brains, along with a few other areas like the lungs and cardiovascular system, while CB2 receptors are abundant in immune cells. The location of these receptors influences the effect that CBD and THC will have on someone.
These molecules support our immune systems and are broken down when they’ve completed their function. There are receptors for endocannabinoids all over the body including the central nervous system (CNS). And as it turns out, THC binds to them and CBD does so weakly or not at all. CBD may in fact reduce the effects of THC by blocking it.
Chewables have to go through the GI tract before entering the bloodstream, so effects take a little longer to kick in with peak blood levels being reached at around three hours after ingestion. This method of consumption has a more prolonged effect lasting up to eight hours. People often over-consume edibles because the results aren’t instant.
In general, substances such as CBD can be detected in hair up to about 3 months after they were last taken. Trace amounts of THC will likely not show up in a hair test.
How Does CBD Affect the Brain?
Regardless of gender, CBD is generally believed to have an elimination half-life of one to two days. This means that half of the dose leaves the body at this time. But how long it lasts is not the same for everyone. Unique factors that determine how quickly CBD is expelled include:
According to the World Health Organization (WHO), pure CBD has no abuse potential. But CBD products can cause psychological dependence. And THC can cause marijuana use disorders and withdrawal symptoms which negatively impact users’ health and productivity.
Taking CBD products with unknown amounts of THC would only yield a valid result if a lab test was done on a blood sample within this short period of time.
As a result, THC and its byproducts are what’s tested for in standard 5-panel and 10-panel drug tests. Pure CBD will not show up on these tests. Tests that can detect CBD are available but they’re more expensive and are not widely used.