Generally, the effects of CBD wear off within just a few hours, but that depends on the amount of CBD taken, the method used, and the user’s size, metabolism, and history of use. If you begin to feel the pain or anxiety begin to return, you can simply take more CBD. There is no practical way to overdose on CBD.
CBD (or cannabidiol) is stored in fat cells in your body, and theoretically can remain detectable for days or even weeks in a blood test. However, research on how long CBD oil stays in the system is spotty, because there’s no real demand for testing. Few employers care if employees consume a non-intoxicating drug that is used mainly to treat pain and anxiety—and commercial testing protocols don’t measure CBD anyway.
CBD disappears from the body relatively quickly. In a study following 14 patients who were each given about 700 mg of CBD a day orally for six weeks, the average plasma level fell to just 1.5 ng/mL a week after the final dose, and was undetectable after that. The authors estimated the CBD half-life to be about 2-5 days.
How long does CBD keep working?
It generally takes 5.5 half-lives for a drug to be fully eliminated from the system. So CBD taken orally would completely leave the body in about 11-28 days, but it may be impossible to detect on a blood test well before that. The half-life for vaped or smoked CBD in blood plasma is much shorter than for ingested CBD—just a few hours. A regular user may take longer to fully clear CBD from their system than an occasional or new user.
Because inhaled CBD reaches the brain rapidly, users may feel a much more immediate and pronounced effect than they would from tinctures or edibles. But the therapeutic effects—reduced inflammation, pain and anxiety—are eventually noticeable from all forms of consumption, assuming you use enough. Proper CBD dosing can require some experimentation.
The non-intoxicating compound CBD is known to have a variety of beneficial effects, including reduction of pain and inflammation, and anxiety relief. A single dose of CBD may keep working for several hours, and the cannabinoid may persist in the body for days or weeks. How long CBD effects last depends on several factors, including the user’s metabolism and if they use CBD regularly.
Research showing how long CBD is detectable in urine is rare, but one study showed a single test subject maintained detectable CBD in his urine for only 24 hours. In any case, CBD is almost never included in standard drug tests (like those given by employers).
Bottom line: Existing evidence suggests that CBD reaches peak blood concentration within three minutes after inhalation, meaning any effects should be felt shortly after use. The effects should then last anywhere from 45 minutes to a couple of hours.
It’s important to note that, while existing evidence shows us that CBD can definitely be detected in the body for a certain period of time, most drug tests specifically look for the presence of THC. Therefore, accurate information on how long CBD stays in the body remains limited compared with information on THC.
Bottom line: While the time that CBD is detectable in the body will depend on the aforementioned factors, we can deduce that CBD will likely leave the system after a week or two.
Bottom line: Apart from the one study that showed CBD was no longer detectable in urine after 24 hours, there isn’t much research on drug testing for CBD in urine.
Bottom line: Whether you’re ingesting CBD oil or CBD-infused edibles, it ultimately goes through the same lengthy digestive process, reducing the total CBD concentration in the bloodstream. With ingestion, it could take anywhere from one to two hours before the effects of CBD finally set in. From there, you may feel the effects for one hour to several hours, depending on the dose and your response to CBD.
CBD may not produce the same intoxicating effects as THC, but it does get stored in the body. The time that CBD remains detectable in the body depends on several factors.
Oral ingestion is the most common method of CBD consumption. Administering a couple of drops of CBD oil directly into the mouth is certainly a convenient way to reap the potential benefits of this therapeutic cannabinoid. However, ingestion is not necessarily the most effective consumption method for those who want to feel the effects of CBD immediately.