CBD edibles, capsules, tinctures, vaporizers, flower and topical creams are all methods for taking CBD, and each has its own time for onset and duration of effects.
There really is no universal answer to how long CBD will last in your body. With many factors playing a part in CBD’s duration and onset of effects, it can impact each person a bit differently. By keeping initial dosages low, you can see how you respond before fully adopting a regular CBD oil routine.
Factors that Affect How Long CBD Lasts
This increased interest in CBD oil has raised many questions, with one of the most common being, “how long does CBD last?” If you’ve never taken CBD before, knowing how long its effects will linger is important for determining your ideal dosage, and ultimately helping you decide if CBD oil is right for you.
Depending on the product you use and your individual biochemistry, CBD oil can remain in the system anywhere from 30 minutes to 2 days.
If you take CBD regularly, the reverse tolerance you build could cause you to feel its effects for a shorter perceived amount of time.
A 1991 study published in Pharmacology Biochemistry & Behavior examined the concentration of CBD in the blood after high doses daily. Over a six-week period, the research team administered a daily dose of 700 milligrams of CBD to 14 Huntington’s disease patients. One week after the dosing ceased, the CBD remaining in the blood was just 1.5 nanograms per milliliter and was “virtually undetectable” thereafter.
Inhalation, via CBD vapes or smokable flower, is also an effective delivery method for CBD. Photo by: Gina Coleman/Weedmaps
Studies show that when the liver metabolizes CBD compounds, they undergo what is called the “first-pass effect.” Enzymes in the liver reduce CBD concentration before the remainder is finally sent to the bloodstream and circulated throughout the body. While oral consumption of CBD has become popular for its ease of use, it can be an inefficient method of consumption compared with inhalation or sublingual administration. This is because only about 5% of swallowed CBD ends up in the bloodstream, meaning this method provides low bioavailability.
Bottom line: Apart from the one study that showed CBD was no longer detectable in urine after 24 hours, there isn’t much research on drug testing for CBD in urine.
Oral ingestion is the most common method of CBD consumption. Administering a couple of drops of CBD oil directly into the mouth is certainly a convenient way to reap the potential benefits of this therapeutic cannabinoid. However, ingestion is not necessarily the most effective consumption method for those who want to feel the effects of CBD immediately.