The general recommendation is to start low and slow. Take the minimum dose based on your weight — 2–6 mg per every 10 pounds of your body weight — and observe the effects over the course of one week. Adjust the dosage as needed and continue for another week. Once you’ve found the sweet spot, you can lock that dosage in and stick to it, as people don’t build a tolerance to CBD.
Cannabis compounds such as CBD are known to modulate the immune system. They act as regulators, bringing an over or under-reacting immune system back on track. However, it’s difficult to tell the difference between “immune-modulating” and “immune-boosting.” It’s commonly agreed that people with autoimmune conditions are better off without taking anything which boosts the immune system.
Clinical dieticians recommend herbs and foods that produce modulatory effects in the immune system for people with autoimmune diseases. Cannabis therapy and dietary changes appear to be less expensive, safer, and possibly more effective for treating the symptoms and addressing the root cause than pharmaceutical medications.
How to Find a Trustworthy CBD Brand?
At some point, the ECS becomes deficient in cannabinoids, compromising the activity of other systems and organs (2).
Cannabinoids are described in scientific literature as novel anti-inflammatory drugs based on preclinical evidence (7). But in order to benefit from cannabinoids, you need to choose a product from the right source.
Long story short, CBD can help the immune system return to homeostasis, provide protection against damage from AI attacks, slow down excess T-cell production, and prevent future attacks.
Still, if you’re considering taking CBD for your autoimmune condition, consult the idea with a holistic doctor experienced in cannabis therapies. Only then will you be able to determine if CBD oil will be safe for your situation.
1. Zuardi AW, et al. Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Braz J Med Biol Res. 2006;39(4):421–429. doi: 10.1590/S0100-879X2006000400001. [PubMed] [Cross Ref]
Cannabinoid molecules, named endocannabinoids, form in the human body as well as all other vertebrates and owe their name to chemical structure similarities they share with cannabinoids in hemp. The endocannabinoids in our bodies function as intercellular lipid messengers that are released from one cell membrane, activating the receptors on the membrane of another cell. Their signals are retrograde because they move, or more accurately, exchange materials and communicate opposite to the usual direction of the intercellular signals. This behavior is what makes them an active substance, lowering the secretion of insulin in the bloodstream, reducing pain and temperature and calming the immune system.
CBD or cannabidiol is a compound found in hemp leaves and flowers whose production and use is completely legal in Slovenia. CBD has many beneficial effects on the human organism and does not cause intoxication – it has no psychoactive effects on a person. CBD is a cannabinoid molecule very similar to the molecule that can be found in the human body, responsible for communication between cells.
Cannabinoids are messengers
Hemp is gaining popularity on a daily basis. This controversial plant, which many still associate with illegal substances, carries a veritable treasure trove of substances that have a soothing effect on a variety of problems. It is also becoming increasingly popular in the field of medicinal uses. Numerous clinical studies and scientific papers reported positive results in therapies involving cannabis resin. The best-known ingredient of cannabis resin is the CBD cannabinoid that proved effective in the field of various auto-immune disorders, Alzheimer’s and Parkinson’s disease. It also recorded positive effects with Crohn’s disease, insomnia, diabetes, depression, and several others. CBD oil is also effective in the field of skin problems, calming autoimmune reactions on the skin and reducing sebum secretion from the sebaceous glands.
2. Demuth DG, Molleman A. Cannabinoid signaling. Life Sci. 2006;78(6):549–563. doi: 10.1016/j.lfs.2005.05.055. [PubMed] [Cross Ref]
Our body is capable of producing the message-transmitting cannabinoids on its own, however, when our body is sick, tired or under severe stress, the production stops and we no longer produce our own cannabinoids. In such cases, we can assist with an input of phytocannabinoids. These can be found in hemp, with CBD being the most researched one. Hemp cannabinoids bind to the same receptors as cannabinoids produced in our own bodies. This makes the body recognize and accept them as its own. Cannabinoid receptors are also found in skin cells, which enables CBD to function effectively and locally through the skin as well.
3. Abood ME, Sorensen RG, Stella N, eds. endoCANNABINOIDS. New York, New York, USA: Springer Science+Business Media New York; 2013.