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CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.

Among the few human trials evaluating CBD’s anxiolytic effects was one published in the Brazilian Journal of Psychiatry in 2019. For this study, 57 men were given either CBD oil or a placebo before a public-speaking event. Anxiety was evaluated using physiological measures (such as blood pressure, heart rate, etc.) and a relatively reliable test for mood states known as the Visual Analog Mood Scale (VAMS).

Health Benefits

Human studies evaluating the use of CBD in treating chronic pain are lacking. Those that do exist almost invariably include THC, making it difficult to isolate CBD’s distinct effects.

CBD oil may reduce the risk of heart disease by alleviating hypertension (high blood pressure) in certain people, suggests a 2017 study in JCI Insight.  

CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.

A 2019 study found that people who experience temporomandibular disorder (TMD) may notice an improvement in their condition after using CBD products. TMD can cause pain and stiffening in and around a person’s jaw.

As well as creams, CBD can be present in balms, salves, and transdermal patches.

Peripheral neuropathy

Additionally, CBD skin cream may help with painful joints. The Centers for Disease Control and Prevention (CDC) say that further research will help determine whether CBD products are equally effective as other pain medications, such as ibuprofen, in providing pain relief.

This article highlights the benefits of CBD skin creams and the conditions for which they may be helpful. It also lists some possible side effects and names three specific products that a person may wish to consider trying.

CBD skin creams most often use broad-spectrum CBD, which is CBD with either no THC or only trace amounts.