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cbd salve side effects

The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.

Wendy Rose Gould is a lifestyle reporter with over a decade of experience covering health and wellness topics.

Drowsiness

CBD benefits include the following:

She adds, “[Another difference is that] CBD is derived from hemp and has been classified as a legal substance. Hemp has <0.3% THC. Conversely, cannabis plants such as marijuana are grown to have much higher levels of THC and are still illegal according to the FDA, although individual states vary as to their use.”

It’s important to point out that CBD is not regulated by the FDA and therefore dosages might not be accurate. It’s also difficult to know what an appropriate dose is the first time you try a new product.

CAUTION: CBD should not be taken by people with liver disease or Parkinson's disease.

Studies found evidence, although not high-quality, that cannabis-based medicines reduced long-term nerve (chronic neuropathic) pain. All but two studies used a plant-based THC/CBD mouth spray (the other two used synthetic oral THC).

Another review with meta-analysis of 104 studies evaluated cannabinoids for the treatment of chronic non-cancer pain. Within this review and analysis, the effect of cannabinoids on sleep was also examined. There was low-quality evidence of improved sleep.

Interactions

Studies of CBD are ongoing, but some benefits have been found.

There are two types of cannabis sativa: hemp and marijuana. The hemp plant is the source of CBD used in most products.

Studies are ongoing, but there is evidence that CBD may be effective in reducing anxiety, chronic (long-term) pain like back pain, and insomnia or trouble sleeping.

The dosing of CBD for different conditions is still being studied.

To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).

Medical marijuana is frequently prescribed to people with intractable (treatment-resistant) pain, including those with terminal cancer. There is some evidence that CBD contributes to this benefit.

CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.

How to Calculate CBD Dose

For this study, nine healthy men took either 600 mg of CBD or the same dose of a placebo. According to the researcher, those treated with CBD had lower blood pressure before and after exposure to stressful stimuli (including exercise or extreme cold).

According to the investigators, men provided 300 mg of CBD exhibited less anxiety than those given a placebo. Interestingly, those provided 100 mg or 600 mg of CBD oil did not.

Part of this response could be explained by the way that CBD acts in the brain. In low doses, CBD may act as an agonist to several receptor sites, meaning it acts similarly to surrounding molecules that normally bind to the receptor, enhancing the signalling of those receptor sites. At higher doses, however, too much activity at the receptor site can lead to an opposite effect, negating the beneficial effects of CBD.

Clinical research has shown that CBD oil can trigger side effects. Severity and type can vary from one person to the next.