One major issue is that it’s actually somewhat difficult to create a topical cannabinoid product (containing CBD or THC) that penetrates the skin enough to produce an effect, but not so deep that it gets into the bloodstream, Boehnke explains. If the product does get into the bloodstream—if it’s transdermal rather than truly topical—it could potentially reach the brain, possibly producing psychoactive effects if it contains THC.
The first thing to be aware of is the amount of CBD that a product claims to contain. Because the studies we have about CBD and pain all looked at systemic administration rather than truly local, we don’t really know what the correct dose would be when applied locally. It’s tempting to go for the highest amount you can find, but it’s really up to you since we don’t even know where to start.
First off, we don’t know much about the correct dose of CBD needed for a pain-relieving effect. The doses in the rat studies that were effective were pretty large (for a rat, obviously). And the human participants in the Phase 2 clinical trial we mentioned received 250 mg of synthetic CBD topically per day—as much as many consumer topical CBD products contain in a single jar.
So…is CBD cream just an expensive placebo?
In fact, the most compelling research they found for using cannabinoids for pain came from a large review and meta-analysis published in JAMA in 2015. For the study, researchers looked at results from 79 previous studies of cannabinoids and various medical conditions, including chronic pain. However, of those studies, only four involved CBD (without THC)—none of which were looking at pain. So although we might assume that CBD is doing something to help address pain—according to the studies involving the whole cannabis plant—we don’t have great evidence to prove it.
“There’s really no substitute for doing proper human studies, which are difficult, expensive, and ethically complicated,” Dr. Tishler says. And we simply don’t have them for CBD and pain.
The studies we do have about CBD for pain are all animal studies. For example, in a 2017 study published in Pain, researchers gave rats an injection into one of their knee joints to model osteoarthritis. Rats then either received doses of CBD or saline directly into an artery in the knee joint. Results showed that, after receiving CBD, rats showed less inflammation in the joint area and fewer pain-related behaviors (like shaking or withdrawing the affected paw or not being able to bear weight in that paw) compared to those that received saline.
The lack of regulation has also left the door open for products to be subject to both “contamination and adulteration,” Dr. Tishler says. One study, published in JAMA in 2017, found that almost 70 percent of CBD products—including vape cartridges, tinctures, and oils—sold online did not contain the things they claimed to in the right amounts. That’s why Boehnke recommends only buying CBD products that you can verify (via a certificate of analysis) do contain what they’re supposed to. And Boenhke offers the same advice he does for all cannabinoid products: Start at a low dose and, if you decide to increase it, go slowly. (Start low, go slow.)
In this case, research suggests that CBD is ingested sublingually in order to receive its full benefit.
Although Psoriasis doesn’t have a cure, CBD oil for skin is becoming a popular natural anti-inflammatory that can help reduce the effects of this disease while providing relief from itchiness/irritation.
By offsetting free-radical damage; free radicals cause collagen to break down faster, so ultimately antioxidants are also helping to slow down the process of collagen loss
CBD FOR SENSITIVE SKIN
Acne is a skin condition that occurs when hair follicles are plugged with excess sebum oil and dead skin cells. This blockage causes white heads, black heads or pimples.
In addition, CBD acts as a hormonal balancer, this suggests that CBD can potentially decrease excess sebum oil production; helping reduce the likelihood of future breakouts.
Research can prove that CBD is considered to be an effective all natural anti-inflammatory.
Although the research relating to CBD and its health benefits is in its infancy stages. CBD research continues to suggest that CBD can be beneficial in several ways. However it is important to assess the quality of CBD products by paying close attention to how it was supplied and manufactured. We recommend using a CBD isolate; meaning it is completely absent of ingredients that can potentially cause CBD to be ineffective. Prior to purchasing CBD ensure that you are taking the necessary steps finding the correct potency for your case, taking into account your body weight, tolerance and health issue.