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cbd oil make you high

CBD (Cannabidiol) is often referred to as “medical cannabis”. Discovered in 1940, it accounts for up to 40% of the plant’s extract.

Studies show that CBD oil is beneficial in treating a range of conditions, from anxiety and depression to inflammation, neurological conditions and even cancer. The chemical works in harmony with the body to support the immune system and cell function, fighting free radicals to remove toxins and promote a sense of well-being.

The Endocannabinoid system

CBD oil doesn’t have psychoactive effects like you would experience from smoking or ingesting marijuana, but it does create a pleasant sensation which many people find relaxing. Unlike THC it won’t alter your perception or make you fail a drug test – as long as you are careful that the CBD product you are using is certified.

There are over 113 different chemical compounds – known as cannabinoids – found in the cannabis plant. The two we need to understand when it comes to getting high (or not!) are THC and CBD.

When purchased from a reputable supplier, CBD oil is considered to be absolutely safe to use. As with all health supplements, it’s a good idea to talk to your GP before you try CBD oil, particularly if you are taking any other medication. CBD oil is generally well tolerated but some people do experience side effects including tiredness, dry mouth or reduced appetite.

In fact, a 2013 review of nearly 1,300 studies published in scientific journals found that CBD “can counteract the negative effects of THC.” The review also points out the need for more research and a look at CBD’s effects on THC consumption in real-world scenarios. But the existing data is clear enough that CBD is often recommended as an antidote for those who have inadvertently consumed too much THC and find themselves overwhelmed.

Pain, stress, appetite, energy metabolism, cardiovascular function, reward and motivation, reproduction, and sleep are just a few of the body’s functions that cannabinoids impact by acting on the ECS. The potential health benefits of cannabinoids are numerous and include inflammation reduction and nausea control.

To understand THC vs CBD and how they affect us, you first need to understand the endocannabinoid system (ECS), which helps the body maintain functional balance through its three main components: “messenger” molecules that our bodies synthesize, the receptors these molecules bind to, and the enzymes that break them down.

How CBD and THC interact with each other

Beyond CB1 receptors, THC and CBD bind to several other targets. CBD, for example, has at least 12 sites of action in the brain. And where CBD may balance the effects of THC through inhibiting CB1 receptors, it may have other effects on THC metabolism at different sites of action.

Things get particularly interesting when other cannabinoid and terpene molecules are consumed alongside THC and CBD. Although we are just beginning to understand the isolated effects of cannabinoids such as CBN, CBC, and CBG, their ability to bind to targets in the brain means they could potentially enhance, reduce, prolong, or in some other way modulate the effects of THC.

The most abundant and well-known cannabinoid found in the cannabis plant is tetrahydrocannabinol (THC). It activates the CB1 receptor, an ECS component in the brain that governs intoxication. THC intoxication has been shown to increase blood flow to the prefrontal cortex, the region of the brain responsible for decision-making, attention, motor skills, and other executive functions. The exact nature of THC’s effects on these functions varies from person to person.

But even this interaction is not entirely clear. In a February 2019 study, researchers found that low doses of CBD actually enhanced the intoxicating effects of THC, while high doses of CBD reduced the intoxicating effects of THC.