CBD can take many forms. Epidiolex, the only approved CBD treatment for epilepsy, is an oral solution containing 99% pure CBD.
The endocannabinoid system works to keep the body in a state of equilibrium, maintaining chemical balance and controlling biological functioning, from appetite to motor control, sensory perception, sleep, and inflammation.
The majority of specific case studies from the late 1990s, and the early 2000s focused on the effect of THC/CBD solutions on epilepsy. Due to the psychoactive nature of THC, the eyes of modern medicine turned to CBD.
CBD Oil Dosage for Epilepsy & Seizures
CBD oil is a cannabis extract with high concentrations of CBD. This product can be sourced from both marijuana and hemp, two members of the cannabis plant family.
The earliest studies proving the effectiveness of cannabis compounds in the treatment of convulsions came from animal research from the 1970s. The researchers analyzed the anticonvulsant properties of both THC and CBD oils, concluding that both extracts had substantial effects on mice.
For instance, a 2015 study analyzing the reports from Epidiolex patients from 11 epilepsy centers across the country showed that the frequency of seizures decreased by 36.5% after a 13-week treatment.
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Epidiolex passed enough safety thresholds to warrant FDA approval. In the two NEJM studies, side effects tended to be mild to moderate, with difficulty sleeping, lowered appetite, and diarrhea topping the list. Some participants also had abnormal results on liver function tests, especially at the higher dose (20 milligrams per kilogram).
Before trying CBD, make sure it doesn’t interact with another medication you may be taking. The National Library of Medicine keeps a complete list of potential interactions.
But you’re not finished yet. Not only will you have to choose among forms, but you’ll also have to decide which ingredient formula you would like. There are three main ones:
Broad-spectrum CBD: This labeling means the product contains all of the plant’s components except THC.
Always do your own research, looking for companies that verify all product ingredients via third-party labs. Ask for a Certificate of Analysis. An FDA survey found that many CBD products don’t contain the levels of CBD stated on the label—some had no CBD whatsoever, while others had way more THC than indicated.