CBD oil, or cannabidiol, is a natural compound found in marijuana and another related plant, hemp. Unlike THC, another compound in the marijuana plant, CBD doesn't cause a "high." However, it may help reduce nausea and other unpleasant… Best CBD Oil for Nausea of 2022 Nausea can be a sign of many different conditions. It commonly springs from low blood sugar, migraine attacks, appendicitis, dizziness, the flu, gastroenteritis, Many people across the world use CBD oil to treat a number of conditions. From anxiety and chronic pain to insomnia.
How to Take CBD Oil for Nausea
This article was co-authored by Aimée Shunney, ND and by wikiHow staff writer, Megaera Lorenz, PhD. Dr. Aimée Gould Shunney is a Licensed Naturopathic Doctor at Santa Cruz Integrative Medicine in Santa Cruz, California where she specializes in women’s health and hormone balancing. She also consults with various companies in the natural products industry including CV Sciences, makers of PlusCBD Oil. Dr. Aimée educates consumers, retailers, and healthcare providers about CBD oil through written articles, webinars, podcasts, and conferences nationwide. Her work has been featured at the American Academy for Anti-Aging Medicine, the American Association of Naturopathic Physicians Conference, and on Fox News. She earned her ND from the National College of Naturopathic Medicine in 2001.
There are 13 references cited in this article, which can be found at the bottom of the page.
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CBD oil, or cannabidiol, is a natural compound found in marijuana and another related plant, hemp. Unlike THC, another compound in the marijuana plant, CBD doesn’t cause a “high.” However, it may help reduce nausea and other unpleasant symptoms, like pain and anxiety. If you have nausea due to a medical condition or a medication you’re taking, such as chemotherapy drugs, talk to your doctor about using CBD to get relief.
Best CBD Oil for Nausea of 2022
Nausea can be a sign of many different conditions. It commonly springs from low blood sugar, migraine attacks, appendicitis, dizziness, the flu, gastroenteritis, motion sickness, food poisoning, morning sickness, brain injury, and more.
Nausea is also a common side-effect of chemotherapy and general anesthesia.
While you can have nausea without vomiting, the latter happens very frequently in nausea sufferers. That’s because neuron circuits in the brainstem detect — or are fooled to detect — a toxic substance and attempts to get rid of it from the gastrointestinal tract.
Cannabis, particularly the CBD, has shown a lot of promise in preventing and easing nausea without the side effects induced by pharmaceutical anti-emetics. In this article, I’ll cover the science behind the potential anti-emetic (anti-nausea) properties of CBD along with my top 3 brand recommendations for high-quality CBD oil.
Best CBD Oils for Nausea (Brand Recommendations)
The market is full of different CBD companies selling all sorts of CBD products. Some of them excel in quality, while others leave a lot to be desired.
For those of you who don’t have the time to background-check each brand on the market, here are some of my favorite brands in the CBD space. I’ll cover criteria such as the hemp source, extraction method, cannabinoid spectrum, potency, and third-party testing.
1. Royal CBD
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
- Their CBD comes from American-grown organic hemp
- Available in 4 potency options
- Contains the full spectrum of cannabinoids
- Up to 2500mg of CBD per bottle
- Nice neutral flavor thanks to the premium MCT oil
- Each batch of product was tested in a 3rd-party laboratory
- Free shipping available
- Slightly more expensive than the competition
What I Like About Royal CBD:
Royal CBD is leading the way in manufacturing premium CBD oils — offering products sourced from organically grown US hemp. Unlike many newcomers, this company likes to keep things simple. They offer basic CBD formats, such as CBD oil, gummies, and capsules.
I’ve been using their full-spectrum 500mg CBD oil to help with things like anxiety, upset stomach, and nausea — so far, it’s done an excellent job at making things more comfortable for me.
2. Gold Bee
- Organic hemp grown in California farms
- CO2 extraction
- Broad product selection
- Full-spectrum CBD
- Up to 2400 mg of CBD per bottle
- Sweetened with honey and stevia
- Third-party tested for quality and safety
- Some of the products are in high demand and sometimes out of stock
What I Like About Gold Bee:
Gold Bee is another premium company from California. The founders have spent several years in the superfoods industry before enrolling in the production of hemp extracts. The brand offers two strengths of CBD oil: 1200 mg and 2400 mg. The stronger version delivers a whopping 80 mg of CBD in every milliliter.
These are the best-tasting organic CBD oils out there. Despite being full-spectrum, their flavored options almost completely mask the earthy taste, countering it with fruity notes. In addition, the oils are sweetened with honey and stevia, making flavored CBD extracts a guilt-free way to take CBD — at last!
I’ve been using the 2400 mg bottle for episodes of severe nausea after food poisoning and it greatly reduced discomfort, stiffness, and the urge for throwing up. Overall, the company is my second-favorite right after Royal CBD.
3. Hemp Bombs
- Hemp Bombs uses certified organic hemp from European farmers
- Their CBD isolate is obtained through CO2 extraction
- Each batch is tested in a 3rd-party lab for potency and purity
- Up to 5000mg of CBD per bottle
- Not as high quality as others on this list
- Since this is CBD isolate, there’s no synergy from other cannabinoids
- For most people, such high doses of CBD are overkill
What I Like About Hemp Bombs:
Hemp Bombs may not offer the quality of brands like Royal CBD, but they do a fine job at making 99% pure CBD isolates on a large scale.
The company sells its isolate in every possible form, including tinctures, capsules, vape oils, gummies, topicals, syrups, or even beard products.
Hemp Bombs gives you more affordable CBD extracts at the cost of some quality. Since this is pure isolate, their products lack the much-needed synergy from full-spectrum extracts. Therefore, you may need a higher dose to feel the difference.
But, if you don’t tolerate other ingredients than CBD in hemp extracts, or you’re subject to periodical drug tests at work and can’t test false-positive for THC, an isolate may be your last resort.
- Their CBD is made from Colorado-grown hemp
- Available as full-spectrum CBD or isolate
- Diverse product selection
- Lab-tested for quality
- Very affordable
- Their hemp isn’t organic
- Their website is buggy
- Only natural flavor available
What I Like About CBDistillery:
CBDistillery offers a wide product selection, including CBD oil, gummies, and capsules. All these products are available as full-spectrum or “Zero THC” (pure oil).
The potency range is impressive as well — offering from 250–5000mg of CBD per bottle. Their products are also good for people looking to buy CBD on a budget. Their 250mg bottle costs only $20.
If you only have mild nausea symptoms, this brand offers you the best ratio of price to quality — even though CBDistillery doesn’t grow organic hemp.
What is Nausea
According to the Cambridge Dictionary, “Nausea is a feeling of illness in the stomach that makes you think you are going to vomit.” However, nausea and vomiting are not illnesses, but symptoms of other health conditions, including vertigo, food poisoning, overeating, concussion or brain injury, blocked intestine, infection, and more.
In very severe cases, nausea and vomiting can sometimes be symptoms of more serious diseases, such as liver disorders, central nervous system failures, brain tumors, and certain forms of cancer.
In a physiological sense, nausea is caused by a toxic agent that gets detected by a neuron circuit in the brainstem. That often leads to vomiting as a way to purge the body out of that toxin.
However, that doesn’t mean people get nauseous only after ingesting toxic substances. For example, motion sickness and morning sickness don’t involve a toxic agent; they often result from hormonal and neurological changes in the body.
Nausea can also be triggered by psychological factors such as anxiety, stress, and depression.
Common Remedies for Nausea
There are specific strategies you can employ to alleviate nausea.
According to the Cleveland Clinic, people experiencing nausea should do the following:
- Drink ice-cold drinks
- Eat bland foods; avoid spices
- Steer clear of fried, greasy, or sweet meals
- Eat smaller portions.
- Don’t mix cold and hot foods
- Drink beverages slowly
- Avoid exercise after eating
- Don’t brush your teeth immediately after eating.
- Keep a diversified diet and include foods from all food groups to avoid allergies
The Cleveland Clinic also has some tips for treating vomiting:
- Increase your fluid intake; drink larger amounts of clear liquids (gradually)
- Ensure You’re well-rested
- Temporarily stop taking all oral medications; they can upset the stomach and worsen vomiting symptoms
Aside from these short-term lifestyle choices, people typically use medicines such as Pepto Bismol, Dramamine, and Kaopectate to relieve nausea. If you’re afraid of the potential side effects of these medications, you can try a popular alternative — CBD oil.
Let’s see how CBD may ease or prevent nausea and vomiting.
What Effect Does CBD Have on Nausea?
Cannabinoids may play an essential role in dealing with nausea and vomiting.
A 2014 review of scientific progress regarding CBD from the European Journal of Pharmacology said:
“Cannabis has long been known to limit or prevent nausea and vomiting from a variety of causes. This has led to extensive investigations that have revealed an important role for cannabinoids and their receptors in the regulation of nausea and emesis (vomiting).”
Evidence from experiments shows that CBD can control nausea by acting on the serotonin receptors in the brain. Namely, CBD decreases the release of serotonin, which results in weaker stimulation on the vomiting controls in the brain. With the help of CBD, serotonin in our system becomes balanced and, thus, making it a great help to manage vertigo-induced nausea.
The anti-emetic properties of CBD are also linked to its influence on the CB1 cannabinoid receptors.
These receptors occur in the brainstem, where both THC and anandamide are used.
Studies show that increased production of anandamide, which is the CB1 agonist, relieves the feelings of nausea and reduces the urge to vomit. However, anandamide tends to quickly break down in the presence of the Fatty Acid Amide Hydrolase (FAAH) enzyme.
According to studies on animal models, CBD can block that enzyme and thus make anandamide more available for the body. The same happens when you consume both THC and CBD. THC fools your brain to think there’s more anandamide to use, whereas CBD extends the life of this endocannabinoid and, at the same time, blocks the sites of CB1 receptors that respond to the psychoactive effects of THC.
What Does the Research Say?
The anti-emetic effects of cannabinoids are one of the best-researched areas of their medical applications. Below I give you a list of three high-impact studies underscoring the potential of CBD to relieve and prevent nausea:
A 2002 study published in Neuroreport concluded:
“cannabidiol, a major non-psychoactive cannabinoid found in marijuana and its synthetic dimethylheptyl homolog interfere with nausea elicited by lithium chloride and with conditioned nausea elicited by a flavor paired with lithium chloride. These results suggest that cannabinoids without psychoactive side-effects may have therapeutic value in the treatment of chemotherapy-induced nausea.”
A 2011 research paper published in the British Journal of Pharmacology indicates that:
“The neural mechanisms of nausea are still not well understood. However, the anti-emetic effect of cannabinoids has been shown across a wide variety of animals that are capable of vomiting in response to a toxic challenge.”
In a 2016 report in Pharmacology, the researchers came with the following conclusion:
“Administered subthreshold combines doses of THC or CBDA to significantly suppress acute nausea, but individual doses of CBDA were maximally effective.”
CBDA is the acidic form of CBD that occurs in raw hemp plants.
Why Use CBD Oil for Nausea?
CBD can be either vaporized, smoked, or ingested as drops or edibles. When it comes to nausea — at least from my own experience — I believe that CBD hemp oil applied sublingually is the best option.
Why CBD Oil is one of the best ways to use CBD:
- CBD oil is sourced from hemp, so it has little THC. There isn’t enough THC in hemp plants to make you high. It gives you the health benefits of cannabinoids without the psychoactive side-effects.
- CBD oil is extracted with CO2 and thus yields a clean and potent product with all the beneficial cannabinoids, terpenes, vitamins, and minerals of the source.
- CBD oil is easily absorbed. Since it gets into the bloodstream via a special membrane under the tongue, it starts to act within 15-30 minutes after ingestion.
CBD dosage for nausea can vary between individuals. I always recommend starting with small doses and gradually increasing your intake until you can feel some relief.
What to Look for When Buying CBD Oil for Nausea
Not all CBD oils are created equal. There’s an abundance of mediocre oil on the market. Such products often have lower CBD concentrations than advertised; some of them don’t contain CBD at all. When you buy CBD oil from an inferior vendor, the product may be contaminated with heavy metals or chemical fertilizers — their presence can even worsen your nausea instead of fixing the problem.
Take a look at the list below to make sure you don’t risk your health buying cheap CBD oil.
1. Hemp Source
Hemp absorbs all substances from its growing environment. This means if you want high-quality CBD oil, the hemp used in its production should come from organic farms and be grown in healthy soil without pesticides or herbicides. Organic hemp yields clean and potent extracts that are safe and effective.
Many U.S. companies grow organic hemp, but they don’t certify it because the certification procedure requires a lot of time and money. If you’re not sure how the company sources their CBD, you can ask them in an e-mail or search their website for more details.
The severity of your symptoms will determine the potency of your CBD oil, among other factors, including your weight, metabolism rate, lifestyle, and age. If you’ve never tried CBD before, start with lower potency (e.g., the Royal CBD oil 250mg) and decide whether it does the job or not. If it doesn’t, or the effects come at the cost of high amounts of oil, you may want to try a more potent product.
3. Cannabinoid Spectrum
For nausea, I would recommend full-spectrum products because they give you the benefits of other cannabinoids and terpenes occurring in the extract. Ideally, you should aim at CBD oil that has significant levels of CBDA, which has been shown through some recent studies to have anti-emetic potential.
There are products on the market that combine decarboxylated (active) extracts with raw CBD oil that packs lots of CBDA.
4. Third-Party Testing
Companies have the option to send a batch of each finished product to a third-party laboratory for testing. These laboratories check for the cannabinoid consistency in the extract as well as for potential contaminants. If the sample returns with a negative result from the lab, the product shouldn’t be allowed for sale until the problem is resolved.
Trustworthy manufacturers display their third-party test results to prove their credibility to the customer. Always buy CBD oil from companies that provide lab reports on request.
If you — or someone close to you — suffer from nausea, consult with your doctor to see if cannabinoids may be an effective treatment. There is sound evidence that the endocannabinoid system plays a vital role in regulating nausea and vomiting, so if you’re looking for a natural alternative to pharmaceutical anti-emetics, CBD oil may be your best bet.
Just keep the above buyer’s guide in mind, so you always end up with high-quality CBD oil.
Do you use CBD oil for nausea? Which form of CBD works best for your symptoms?
- Sharkey, K.A., Darmani, N.A, & Parker, L.A. (2014). Regulation of Nausea and Vomiting by Cannabinoids and the Endocannabinoid System. European Journal of Pharmacology, 722, 134–146.
- Van Sickle, M.D. et al. (2001). Cannabinoids Inhibit Emesis Through CB1 Receptors in the Brainstem of the Ferret. Gastroenterology, 121(4), 767–774.
- Parker, L.A., Limebeer, C.L., Rock, E.M., Litt, D.L., Kwiatkowska, M., Piomelli D. (2009) The FAAH Inhibitor URB-597 Interferes With Cisplatin- and Nicotine-induced Vomiting in the Suncus murinus (House Musk Shrew). Physiology & Behavior, 1, 121–124.
- Parker, L.A., Mechoulam, R., Schillevert, C. (2002) Cannabidiol, a Non-psychoactive Component of Cannabis and its Dimethylheptyl Homolog Suppress Nausea in an Experimental Model With Rats. Neuroprotection, 13(5), 567–570.
- Parker, L. A., Rock, E. M., & Limebeer, C. L. (2011). Regulation of Nausea and Vomiting by Cannabinoids. British journal of pharmacology, 163(7), 1411–1422.
- Rock, E.M., Connolly, C., Limebeer C.L., Parker, L.A. (2016) Effect of Combined Oral Doses of Delta(9)-tetrahydrocannabinol (THC) and Cannabidiolic Acid (CBDA) on Acute and Anticipatory Nausea in Rat Models. Psychopharmacology, 233(18), 3353–3360.
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
Best CBD ratio for nausea
Many people across the world use CBD oil to treat a number of conditions. From anxiety and chronic pain to insomnia. You’ll find a huge choice of CBD products online, but not all are created equal. Make sure that you are buying a quality product, like the ones available at Fusion CBD.
As well as being effective at treating a range of symptoms, there is an increasing amount of research to suggest that CBD oil is also effective in treating nausea.
Here is the low down on using pure CBD oil to treat your nausea.
Causes Of Nausea
There are a number of different conditions that can produce nausea as a symptom. Some of these include:
- Food poisoning
- Motion sickness
When and how often you are nauseous could give you some clues as to the cause of it. If you find you’re vomiting after meals, then this could be caused by food poisoning or food intolerance. However, certain other foodborne infections, such as Salmonella, can show up between 8 and 24 hours.
There are also a number of other serious conditions that can result in nausea. You should always have any new symptoms investigated by a doctor before using CBD.
How Does Pure CBD Oil Treat Nausea?
Ongoing research and anecdotal evidence suggest that CBD oil is effective in treating nausea and vomiting. It is believed to work by reacting with serotonin receptors in the brain. Serotonin is a hormone that can promote feelings of wellness and a good mood. It can also reduce the symptoms of nausea in many people.
The American Cancer Society already lists cannabinoids as a way to reduce and manage nausea at home. It has been found to be effective where other ant-emetic drugs have failed and can increase appetite, another issue that people living with cancer sometimes face.
The Best CBD Ratio For Treating Nausea
When it comes to using pure CBD oil to treat any condition, it’s important to know how the compounds in cannabis work and how they affect the body. Not all CBD products are the same and contain different ratios of ingredients.
Cannabinoids come in two main forms. These are tetrahydrocannabinol (THC) and cannabidiol (CBD). It is THC that produces the ‘high’ associated with cannabis and is by law, only found in CBD oil in trace amounts.
Federally legal CBD oil cannot contain more than 0.3% THC. You can only buy higher concentrations in states with a legalized recreational policy or for medical purposes.
Understanding how these chemical works to treat pain and nausea is the first step in finding the right product for you.
Research has shown that higher THC levels are better for treating severe and prolonged nausea, you will need to find the right ratio that works for you. Remember, different people respond in unique ways to CBD oil.
When looking at CBD products, you’ll notice that there is often a ratio listed on the documentation. You’ll most likely see ratios such as 1:1, 5:1 and 10:1. You need to understand what these mean so that you don’t buy a product that is too strong for you or is ineffective.
1:1 – this means that the level of CBD and THC are the same.
5:1 – indicated there CBD is found at levels 5 times more than THC.
Types Of CBD Products & Timings
There are many different ways to ingest CBD. You can take it as a liquid, capsule, gummy or tincture. Some people find the taste of CBD oil unpleasant, so if you’re feeling nauseated or vomiting then drinking something you don’t like the taste of could make you worse. Similarly, if you’re vomiting a lot, then a tincture that you put under your tongue can help it stay in your system longer.
Different types of CBD products take different amounts of time to start working. The most common ones are:
- Smoking/vaping – this is the fastest way to get pure CBD oil into your system, but the effect lasts between 2-4 hours. This can be a good option if you need to feel better quickly while waiting for another, longer-lasting dose to kick in. If you are feeling very nauseated, it could cause you to gag or vomit but this doesn’t affect how it reaches your system.
- Patches/gels – referred to as transdermal, release CBD directly into the bloodstream. It is another way to get quick relief. Most patches start to work between 20mins-1 hour and can slowly release it into your system for up to 12 hours.
- Under the tongue (sublingual) – these can be placed directly under your tongue. However, they don’t always get into your bloodstream through your oral mucosa (soft tissue). Instead, they end up in the digestive tract and can be made less effective by vomiting. They can take between 1-3 hours to start working.
- Gummies – these can be chewed and can take up to two hours to work. They are a good option if you have to carry them around or take them around other people. However, if you vomit, then they may not be effective unless you’ve been able to keep them in your stomach long enough to be absorbed.
- Creams – these are applied directly to the skin and can start working in as little as 20 minutes. The effects don’t last long but you can use it as quick relief while you are waiting for a different CBD product dose to become effective.
Living with frequent nausea can be debilitating and have a detrimental effect on your quality of life. You should always have the cause of recurring nausea investigated by a health professional first in order to rule out any serious conditions.
Many people are finding relief through pure CBD oil. When it comes to the type of CBD product and strength ratio you need, then it can be a case of starting with a low dose to see how well you tolerate it.
Severe chronic nausea can respond better to products that contain low levels of THC (up to 0.3% is allowable by Federal law).