With laws being altered throughout America to allow for medical marijuana use, however, the traditional stigma is rapidly dissipating, and we have to put much of that change down to CBD and its incredible array of benefits.
CBD is one of over 100 cannabinoids produced by the marijuana plant, but unlike the majority of them – which are not known to possess major health benefits on their own – it is known to display nearly all of the medicinal and therapeutic properties of whole-plant cannabis.
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However, the Agriculture Improvement Act of 2018 (aka the Farm Bill) changed all that. The Farm Bill legalized “hemp,” which the legislation defined as cannabis that contains no more than 0.3% THC, in Mobile, Alabama and surrounding areas like Montgomery and Millbrook.
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Crockett J, Critchley D, Tayo B, Berwaerts J, Morrison G. A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects. Epilepsia. 2020;61(2):267-277. View abstract.
Resstel LB, Joca SR, Moreira FA, et al. Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats. Behav Brain Res 2006;172(2):294-8. View abstract.
Liver disease: People with liver disease may need to use lower doses of cannabidiol compared to healthy patients.
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Englund A, Morrison PD, Nottage J, et al. Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment. J Psychopharmacol 2013;27(1):19-27. View abstract.
Aviello G, Romano B, Borrelli F, et al. Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. J Mol Med (Berl) 2012;90(8):925-34. View abstract.
Yamaori S, Kushihara M, Yamamoto I, Watanabe K. Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective potent inhibitors of human CYP1 enzymes. Biochem Pharmacol 2010;79(11):1691-8. View abstract.
Esposito G, Scuderi C, Savani C, et al. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. Br J Pharmacol 2007;151(8):1272-9. View abstract.