So far, though, most larger scientific studies on CBD have been limited to animals. A handful of small human trials are now underway to evaluate the extent of cannabidiol's pain relief potential. Even without clinical trials, many people already use legal CBD to counteract the intense discomfort brought on by chemotherapy, and to ease pain in arthritic joints. Texas-based dermatologist Jennifer Clay Cather, who cares for people with complicated skin problems, says most of her patients come from oncology. She also owns a research company that develops CBD skin products. “We need large, evidence-based trials testing different conditions, and also testing the reproducibility of the molecule,” Cather says.
Pain is a big driver behind opioid addiction. Many people who began treating chronic pain with prescription opioids have switched to heroin when other drugs became difficult to get. A lot of people have died as a result, says Yasmin Hurd , an addiction specialist at the Icahn School of Medicine at Mount Sinai in New York. “We have so many people in our society now experimenting with CBD to manage pain,” she says. “They are going to their clinicians and asking them for CBD.”
Sidestepping the CB1 and CB2 receptors means that CBD can mute pain without the high sensation delivered by THC. Not only does CBD have very little interest in switching on CB1, cannabidiol can actually mute any signals sent to that receptor. Researchers looking for safer pain treatments want to take advantage of this action because it means that CBD won’t spark addiction.
Skin in the Game
CBD is one of the hundreds of biologically active ingredients produced in Cannabis sativa plants. Unlike THC, its psychoactive cousin that makes people feel high, CBD can ease pain without the euphoria or fear of addiction. The cannabinoid has similar effects whether absorbed through the skin or ingested by mouth.
Consumers need to be educated, as well, says Cather. She works to develop a trusting relationship with her patients, so that they’ll feel comfortable talking about using CBD. She also urges her patients to find companies that document what’s actually in the bottle or jar. Asking the company about their quality control, such as how often they document ingredients, can help also vet the product.
Researchers have confirmed that CBD works against pain and inflammation , and they’re still finding new ways that it works in the body . They're also working to nail down the proper dose of topical CBD needed for pain relief. For example, the dose that brings relief to achy joints may be insufficient to effectively treat nerve damage in feet. While rubbing topical CBD onto the skin seems to work, researchers still need to figure out how much skin coverage is most effective. Some skin creams also contain menthols, which carry their own pain relief and anti-inflammatory properties, possibly masking any effect from the CBD itself.
Consumers aren’t waiting for clinical trials. But they need to remember, says Hurd, that slathering on creams can be risky, considering how the skin absorbs everything. Even topical CBD can react with oral medications.
Hemp pain relief creams or cannabis lotions claim to offer muscle relief for your tired body, but what do experts have to say?
Interest piqued? Learn more about hemp cream for pain relief and all its variations.
What Is Hemp Pain Relief Cream?
The fatty tissue can only hold so much oil, so, theoretically, if you apply enough of a cannabis cream to your skin, it might leak down into your skeletal muscle just out of diffusion, adds Sexton. But there's no study to show this, and that means you're going to be rubbing on a whole lot of the stuff.
The other issue? Topical hemp pain relief products and cannabis creams will treat anatomical structures within 1 centimeter of the skin—and the muscle where your actual soreness is located is going to be deeper than that, explains Ricardo Colberg, M.D., a physician at Andrews Sports Medicine and Orthopaedic Center in Birmingham, AL. (The good news: Since it doesn't need to be absorbed deeply, CBD and cannabis could do amazing things as a skincare ingredient.)
Science has shown that cannabis is an effective pain reliever, reinforced in a massive new report from the National Academies of Sciences, Engineering, and Medicine. But there's a big difference between ingesting cannabis or its individual chemicals orally and absorbing it topically through your skin.