All in all, Xyrem probably isn’t the best drug to mix with CBD. The results of both substances as depressants on the central nervous system can lead to dangerous levels of CNS depression. It’s better to follow the medication plan you have in place with Xyrem than to add in CBD.
At the bare minimum, they recommend talking to a healthcare professional such as a doctor or at the very least a pharmacist before taking anything with Xyrem.
If CNS depression becomes particularly threatening, it can lead to delirium or even a coma. If more severe symptoms appear, it’s important to seek immediate medical attention.
Concerns of Misuse
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Mild CNS depression can give someone the same feeling of taking a sedative. You might feel more tired, your speech pattern might become slow or slurred, or you might lose a little coordination. These aren’t severe reactions and they’re probably what you feel when you take a medication like Xyrem or a sleeping medication.
Xyrem works as a CNS depressant because its goal is to help avoid daytime sleepiness by providing deep sleep at night. It also works to suppress the nervous system to avoid cataplexy. This is involuntary muscle movements resulting from a strong emotional response such as joy, anger, fear, or surprise.
If you are on Xyrem, you might be wondering if CBD can help your symptoms. Before combining CBD with any medication, however, it’s important to find out if there will be any negative side effects or if it’s safe to take at all.
Cigar hollowed out with marijuana added: Blunt
Central Nervous System Depressants
Low doses: slight increase in breathing rate; increased blood pressure and heart rate; shallow breathing; face redness and sweating; numbness of the hands or feet; problems with movement.
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An emerging family of drugs containing one or more synthetic chemicals related to cathinone, a stimulant found naturally in the khat plant. Examples of such chemicals include mephedrone, methylone, and 3,4-methylenedioxypyrovalerone (MDPV). For more information, see the Synthetic Cathinones DrugFacts.
Benzos, Downers, Poles, Tranks, Totem Z-Bars, Vs, Yellow/Blue Zs, Zannies
Concentrates: Budder, Crumble, Shatter, Wax
Older adults: higher risk of accidental misuse because many older adults have multiple prescriptions, increasing the risk of drug-drug interactions, and breakdown of drugs slows with age; also, many older adults are treated with prescription medications for pain.