Furthermore, THC remains a Schedule I drug under the Federal Controlled Substances Act, and only hemp-derived CBD produced under the regulations of the 2018 Farm Bill is legal.
When considering a CBD oil product for pediatric care, look out for signs of a reputable brand on product labeling and watch out for buzzwords with no scientific value or definition, such as “organic,” “pure,” or “natural.” In the United States, the U.S. Food and Drug Administration (FDA) doesn’t currently allow CBD oil labels to make claims of curing or treating diseases and conditions. All reputable CBD products have a certificate of analysis available from the manufacturer or company’s website.
CBD’s interaction with the body through these receptor pathways is complex, which is why the potential benefits of CBD vary widely, both in terms of potency and type of effect. The chemical makeup of the various types of CBD oil, including the actual dosage within the product, will also alter the potency and probability of noticeable effects. CBD oil typically falls into one of three product categories:
Safe consumption methods for children
The extent to which the effects of CBD oil differ between adults and children remains largely under-researched. Because the nature of CBD absorption varies significantly from patient to patient, and research into pediatric use of CBD is still limited, the precise differences in response between adult and child patients are also difficult to pin down.
CBD modulates interactions that take place at cannabinoid receptors, which helps it elicit therapeutic effects. Photo by: Gina Coleman/Weedmaps
When dosed properly, relatively safe consumption methods of CBD include tinctures, drops, and capsules. Children should generally be given CBD oil orally, as opposed to adult-use methods such as vaporizing and combusting high-CBD cannabis flower. Epidiolex is a cannabis-derived oral medicine with CBD as the active ingredient, approved by the FDA for use in treating epileptic seizures in patients ages 2 and older.
CBD oil — a concentrate, tincture, or cannabis extract with a high concentration of cannabidiol (CBD), whether extracted from marijuana or hemp — is a rising health and wellness trend and one of the most speculated-about products. A couple of factors have contributed to the rise of CBD oil in the 21st century, namely the essential-oil boom in the wellness market, and the growing field of research which attributes many of the most sought-after medicinal effects of cannabis to CBD.
Very little controlled research has been done with CBD and kids. There is only one approved drug based on CBD for any age group, and that’s for rare kinds of epilepsy in children. There are promising hints — but little proof thus far — that the compound might work on some other conditions in children too, including other kinds of seizures, autism and anxiety.
In addition, Adelaide’s doctors began to see signs of liver failure. Cervantes took her off the CBD. She said CBD, “does not come without side effects, which I think is a major misconception about it.” In trials of Epidiolex, a moderate dose caused side effects in at least 10 percent of the children, including elevated liver enzymes, decreased appetite, diarrhea, fatigue, sleep problems and malaise.
Hints of help
More Americans are using the hemp (or marijuana) extract on their kids, but experts aren’t sold on its efficacy.
“When you’re desperate, you want options,” said John Mitchell, clinician at Duke ADHD Clinic in Durham, N.C. “I’m a parent myself. I get it.” But, he cautioned, for now the enthusiasm is running ahead of the science. “I’m very hesitant to say anything promising about it. It’s an open question.”
That matches Batista’s experience. “My daughter has a beautiful personality; she’s sweet, she’s spunky. I don’t want to medicate her with something that’s going to turn her into a zombie,” she said, referring to parent complaints that some stimulant-based drugs can make their kids seem spacey.