As it stands, all reputable sources on CBD side effects do not list panic attacks as one of them, such as Mayo Clinic or WebMD, albeit VeryWellHealth does highlight anxiety as a potential issue. There is a fascinating post on Reddit about someone who had a panic attack after taking CBD oil, of which there are 23 comments, largely made up of people who are in a similar situation.
I surveyed 300 of my regular visitors to ask them if they have had a panic attack after taking CBD oil and a terrible 14% said yes! That is quite substantial. To the people that said yes, I asked whether this has continued when using another product and 93% said no, meaning it could be down to a bad batch. Once again, this is why greater regulation is required.
The reality is, after labs have tested various CBD products, they have often found levels of cannabinoids to be off what they state, while traces of other ingredients have occasionally been found. This can also vary drastically with each batch.
THC, the other well known cannabinoid found in cannabis that is notoriously known for being psychoactive, has been shown in numerous studies to cause anxiety and can cause a panic attack. CBD, on the other hand, works well together to counter this effect and prevent a panic attack, working together causing the entourage effect.
It could possibly be down to the quantity of THC being higher than stated. THC can’t be sold in the UK for levels higher than 0.2%, however the products often don’t match the 3 rd party lab test results, making it incredibly difficult to know if you’re getting what it says on the tin.
Now, I don’t want to spread fear at this point, but we put a huge amount of trust in brands that are producing products labelled as a dietary supplement, without proper regulation in place. This is one of the biggest reasons why I started CBD Sloth, to make CBD brands accountable and to test it for others so they could feel more assured of what to try.
If you found you’re having a panic attack, you should always seek medical advice. But one added option could be to try a CBD isolate, which has zero THC.
CBD seems to be a promising drug for the treatment of PD. However, novel clinical trials involving patients with the PD diagnosis are clearly needed to clarify the specific mechanism of action of CBD and the safe and ideal therapeutic doses of this compound.
Panic disorder (PD) is a disabling psychiatry condition that affects approximately 5% of the worldwide population. Currently, long-term selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for PD; however, the common side-effect profiles and drug interactions may provoke patients to abandon the treatment, leading to PD symptoms relapse. Cannabidiol (CBD) is the major non-psychotomimetic constituent of the Cannabis sativa plant with anti-anxiety properties that has been suggested as an alternative for treating anxiety disorders. The aim of the present review was to discuss the effects and mechanisms involved in the putative anti-panic effects of CBD.
Regarding the parahippocampal gyrus, although its deactivation has been observed after panic attacks induced by lactate  or cholecystokinin-4 , spontaneous panic attacks have also been associated with the activation of this area . Because the study of Crippa and colleagues 
Aiming to investigate the role of dPAG in the panicolytic-like effect of CBD, Soares and colleagues  injected different doses of CBD (30–60 nmol, 0.2 μL) into the dPAG and successfully inhibited escape responses generated in two animal models: the electrical stimulation of the dPAG and the exposure to the open arm of the elevated T-maze. In addition, the anti-panic effects of the chronic treatment of CBD, observed in animals tested in the elevated-T maze, are mediated by serotonergic mechanisms located in the dPAG .
i.p. – intraperitoneal; i.c.v- intracerebroventricular; s.c- subcutaneal, BNST- bed nucleus striaterminalis, PAG- periaqueductal grey matter, CBF- cerebral blood flow; AEA- anandamide.