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can cbd isolate dissolve in canola oil

Why would anyone choose to make their own CBD oil, when there are so many amazing brands on the market? Well, for the same reasons that people cook at home, and even grow marijuana at home. The benefits come down to price, quality control, and potency.

Turn off the stove and let the mixture cool down in the same pot. Once the oil is cool, then you can transfer the oil into another container and store it at room temperature.

Add 1 cup of your carrier oil to a pot. Put the pot on the stove, on low heat, and wait for the oil to simmer. You’ll know it’s ready when it starts to form small bubbles on the bottom of the pot. Then, crush 1 gram of your CBD crystals or concentrate into a powder form, and put the concentrate into the pot. Now, stir the mixture until the CBD has completely dissolved. To know your CBD is completely dissolved, there should be no more powder or chunks of crystal in the oil. If you notice that your crystals are not dissolving entirely, you can also use a cheesecloth to strain the oil and remove the excess crystals.

The Downside of Making your own CBD oil

Making CBD oil at home is actually a lot easier than it might seem. Once you understand the basics and have the right tools at your disposal, there’s not much standing in your way from creating your own personal batch of the good stuff.

Your homemade CBD oil can be applied directly onto your body to ease sore muscles, itchiness, or chronic pain. If the texture of the oil is not to your liking, you can also mix some CBD oil into a cream or salve and apply it the same way you usually would.

The last thing you’ll need is a large pot and a stove or burner.

Once you have the CBD content, it’s time to choose a carrier oil. Depending on your preferences, you can select virtually any type of oil, but most people use either coconut oil, olive oil, or canola oil. If you want to use this CBD orally, it’s best to choose a carrier oil that you won’t mind tasting. If your main priority is for topical use, coconut oil works great on the skin and is not as pore-clogging as canola oil or olive oil.

Ostwald ripening is a destabilization process, through which larger oil droplets in a nanoemulsion grow at the expense of smaller ones. This occurs because the difference in Laplace pressure causes smaller oil droplets to have higher local solubilities than the larger ones [6]. The rate of this process is mainly defined by the aqueous solubility of the oil [7]: the quicker the oil is able to diffuse between the droplets through the water phase, the faster will be the Ostwald ripening process. The solubility of cannabinoids in water averages to approximately 0.0015 mg/ml [8], which is too low for efficient delivery into the body, but high enough to cause rapid nanoemulsion destabilization through Ostwald ripening.

As explained earlier, nanoemulsions must have small droplet sizes (< 300 nm) in order to be kinetically stable [3] and provide high bioavailability [1]. It is well-known in the pharmaceutical and food industries that the smallest nanoemulsion droplet size is achieved when the dispersed phase (oil) and continuous phase (water) have similar viscosities [4]. The viscosity of cannabis extracts, however, is generally much higher than that of water, which leads to the formation of emulsions with much larger droplet sizes than required (Fig. 1). A carrier oil can help bring down the overall viscosity of the dispersed phase, making it easier to produce nanoemulsions with very small droplet sizes [5].

Droplet size reduction: improves stability and bioavailability

[1] H. Yu, Q. Huang, Improving the oral bioavailability of curcumin using novel organogel -based nanoemulsions, J. Agric. Food Chem., 60 (2012) 5373-5379.

As a general rule, the amount of carrier oil in your formulation should somewhat exceed that of the cannabis extract or isolate. 50 – 60% of LCT in the oil phase is generally sufficient to prevent Ostwald ripening [7] as well as to help achieve the smallest droplet size (Fig. 3) [5].

This is a second article in the series on the principles of formulating water-compatible cannabis extracts and isolates, also known as water-soluble CBD and THC. The first article showed multiple advantages of nanoemulsions over the other two water-compatible formulation classes: microemulsions and liposomes. Here I will demonstrate the importance of using a carrier oil in your cannabis extract or isolate nanoemulsion. I will also explain how to select the proper carrier oil among the available choices.

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